Important points to remember about DMT include:
- The drug naturally occurs in plant leaves and in human and animal brains, and can also be made in a lab.
- It can cause complex visual hallucinations.
- A high from the drug generally lasts only about 45 minutes.
- The drug is a Schedule I controlled substance in the United States.
Ohio newspaper headlines are full of stories about people being arrested and charged for making a drug called DMT. In 2018, a young man even died from drinking tea containing the drug at an Ohio church. But what is DMT, and why are people being arrested for making it and dying from using it?
What Is DMT?
N,N-Dimethyltryptamine, or DMT, is a chemical present in plant species around the world. It has been used in rituals for hundreds of years. The drug can also be created in a lab. Scientists think DMT is naturally created in small amounts in human and animal brains as well. The body creates DMT using the amino acid tryptophan, which is contained in many foods.
The drug is best known for causing hallucinogenic trips. These effects occur because of how DMT impacts certain brain chemicals, namely serotonin. The drug has its main effect on areas of the brain that control perception, like the prefrontal cortex.
Legally, DMT is classified as a Schedule I controlled substance in the United States. This means that it has no accepted medical use and a high potential for abuse. It is illegal to make or possess DMT. Chemically, DMT is a hallucinogenic drug. Other drugs within the hallucinogenic classification include salvia, LSD, and psilocybin.
What Does DMT Do?
The drug is best known for getting into the brain and causing powerful and complex visual hallucinations. These tend to begin seconds after taking lab-created DMT and can last up to 45 minutes. However, visuals from plant leaves may last longer. In DMT visuals, an entirely separate reality is created in the mind of the person taking it. Sometimes, this reality is superimposed over what the person is seeing in the real world. This can lead the person to experience two different realities at the same time. While some people have reported these visuals are pleasant, others have described them as terrifying.
Dosage and Administration
Dosing for DMT can vary. When people have taken the drug in medical studies, they started hallucinating at the very low dose of 0.09mg per pound of body weight. However, usual DMT doses when used as a street drug may be higher, around 40 to 50mg, when smoked or inhaled.
People can use DMT in different ways. Most people do not take DMT by mouth unless they are drinking it in a brew such as ayahuasca tea. This is because DMT is not easily absorbed by mouth unless it is taken with chemicals that inhibit an enzyme called monoamine oxidase. Brews with leaves that have DMT may contain such a chemical, however, DMT from a lab does not. Therefore, the drug is often instead smoked, snorted or injected.
What Does DMT Look Like?
When created in a lab, DMT is a white crystal which can be crushed into a white powder. In turn, the powder may be put into capsules. When taken from natural sources, DMT is often brewed from leaves. A variety of plants contain DMT, and therefore the appearance of leaves with DMT may vary.
Other Names & Street Names for DMT
Many of the street names for DMT refer to the short duration of its high. For example, people started calling it “businessman’s trip” because the high might last about as long as a business lunch. Nicknames for DMT include:
- 45-Minute Psychosis
- Businessman’s special
- Businessman’s trip
Side Effects of DMT
The drug can cause both psychological and physical side effects. Although the mind-altering effects of DMT are best known, some of the physical effects can be serious and even deadly. Some side effects of DMT are:
- Complex visual hallucinations
- Distorted hearing
- Changes in how you sense time
- Changes in how you sense your body
- High blood pressure
- Fast heart rate
- Wide pupils
- Rapid eye movements
- Muscle coordination problems
- Respiratory arrest
Using DMT While Pregnant
You should not use DMT if you are pregnant. While DMT has not been studied in pregnant humans for ethical reasons, it has been studied in animals. These animal studies have shown a risk of birth defects when DMT is used while the animal is pregnant. Birth defects linked to DMT include:
- Cleft palate
- Skeletal deformities
How Long Does DMT Stay in Your System?
The drug can stay in your body for different amounts of time, depending on what is being tested. It is important to remember that doctors think the human body makes small amounts of DMT on its own. Therefore, a trace amount may always be present. However, DMT is known to show up in parts of your system like:
- Blood: DMT lasts in blood less than 15 minutes.
- Urine: DMT stays in urine at least 24 hours.
- Hair: DMT can show up in hair, but little data exists about how long it stays there.
Is DMT Addictive?
Doctors are not sure if DMT is addictive. But they do know that addiction has a close relationship with tolerance and physical dependence, neither of which is linked to DMT. According to current research, people who take DMT do not become tolerant to it. This means that they do not need to steadily increase the dose of the drug to keep getting high. Further, people who take DMT do not usually become physically dependent on it, meaning that withdrawal is rare.
If you or a loved one struggle with hallucinogens including DMT, help is here. Contact us at The Recovery Village Columbus and learn how we can help you lead a life without substance use.
Perry, Parker. “Man Indicted in Clark County Drug Manufacturing Case.” Springfield News-Sun, March 12, 2019. Accessed August 17, 2019.
The Morning Journal. “Lorain Police Arrest Three on Multiple Drug Charges.” April 23, 2019. Accessed August 19, 2019.
Ray, Karla. “No Charges Filed After Death at Ayahuasca Church.” Dayton Daily News, October 13, 2018. Accessed August 19, 2019.
Drug Enforcement Administration. “N,N-Dimethyltrypamine.” Published November 2016. Accessed August 19, 2019.
Barker SA. “N, N-Dimethyltryptamine (DMT), an Endoge[…]ts Role and Function.” Published August 6, 2018. Accessed August 19, 2019.
National Institute on Drug Abuse. “Hallucinogens and Dissociative Drugs.” Updated February 2015. Accessed August 19, 2019.
dos Santos RG, Bouso JC, Hallak JEC. “Ayahuasca, Dimethyltryptamine, and Psych[…]iew of Human Studies.” Published April 2017. Accessed August 19, 2019.
Vitale, Arturo A. “In Vivo Long-Term Kinetics of Radiolabel[…]amine and Tryptamine.” Journal of Nuclear Medicine, June 1, 2011. Accessed August 19, 2019.
Pichini, Simona; et al. “Ultra-high-pressure Liquid Chromatograph[…] Mushrooms Consumers.” Journal of Pharmaceutical and Biomedical Analysis, November 2014. Accessed August 19, 2019.
Strassman R. “DMT: The Spirit Molecule: A Doctor’s R[…]Mystical Experiences.” Published 2001. Accessed August 19, 2019.
Davis, Kathleen. “Everything You Need to Know About DMT.” Medical News Today, March 24, 2017. Accessed August 19, 2019.
Carbonaro, Theresa M; Gatch, Michael B. “Neuropharmacology of N,N-Dimethyltryptamine.” Brain Research Bulletin, September 2016. Accessed August 19, 2019.
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